Academic Qualification: PhD
Date of Birth: 18th July, 1955
Birth Place: Kayela Mbeya
Nationality: Tanzanian
Publications: 21 Original research papers in international journals with impact factor > 1.0
Selected Publications (5):
1. JM. Sayi and BE Leonard.tudies on the nootropic potential of some angiotensin converting enzyme ihibitors in the rat. Prog. Neuro Psychopharmacol, Biol. Psychopharmacol, Biol. Psych. 13/16, 1989, 953-962.
2. Sayi JG; Patel NB; Gatere S; Matuja WBP. Et al Apolipoprotein E. alleles in elderly East Africans. Neurology of Aging 1996: 17: (45) 1 123-126.
3.·Collet Dandara; Collen Masimirembwa; A. Magimba; Jane Sayi et al.Genetic polymorphism of CYP2D6 and CYP2C19 in East and Southern African populations including psychiatric patients. Eur J Clin. Pharmacology (2001).57: 11-17.
4.·A.Wennerholm, Collet Dandara, Jane Sayi et al.The African specific CYP2D6*17 allele encodes an enzyme with changed substrate specificity Clinical Pharmacology and therapeutics Jan 2002 71; 77-88.
5.·A.Mirghani; Jane Sayi; Annika Allqvist; Mary Jande; Agneta Wennerholm; Jaran Eriksen; Lars L. Gustafsson and Leif Bertilsson.CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity compared to a Swedish population.

Short Write-up: Doctor Jane Sayi was born in 1955 in Tanzania. She did a Doctor of Medicine Degree in 1976-1981 at the University of Dar-Es Salaam. After a one year Internship at the Kilimanjaro Christian Medical centre (9181-82), she worked as a Tutorial Assistant in the department of Clinical Pharmacology. She then left for Ireland where she did her PhD degree in 1984-1987 at the University of Collage Galway. She returned to the Department of Clinical Pharmacology and rose through the ranks from Senior Lecturer to her current position as Head of the Department from 2000. She has also a been the A s s o c i a t e D e a n ,Undergraduates, Faculty ofMedicine, MUCHS for 3 years (1997-2000). She has research interests in Alzheimer’s disease malaria and genetics (CYP450 enzymes). She has 21 publications mainly on genetics.
Dr. Jane Sayi is an extremely efficient collaborator. She has facilitated very productive collaborations with the African Institute of Biomedical science and Technology and with the Karolinska Institute in Sweden. These collaborations have resulted in the training of several postgraduate students and publications in high impact journals. Her skills at getting things done even under sometimes very difficult circumstances makes her a unique leader that Africa needs in defining and exploring new biomedical fronts. She has co-coordinated research in the pharmacogenetics of drug metabolizing enzymes and in bio-analysis of anti-parasitic drugs which have contributed to Tanzania being one of the leading countries in these studies in Africa.